Di phthalate cancer

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August undefined, 2024

Web(0.3 mg/L) would result in not greater than a one-in-ten thousand increased chance of developing cancer. For a detailed discussion of confidence in the potency factors, … WebDiisononyl Phthalate (DINP) Why am I being warned about potential exposure to DINP? DINP is on the Proposition 65 list because it can cause cancer. Exposure to DINP may increase the risk of cancer. Proposition 65 requires businesses to determine if they must provide a warning about exposures to listed chemicals. What is DINP?

Phthalates - Proposition 65 Warnings Website

WebDi (2-ethylhexyl) phthalate is produced commercially by the reaction of excess 2-ethylhexanol with phthalic anhydride in the presence of an acid catalyst such as sulfuric acid or para -toluenesulfonic acid. It was first produced in commercial quantities in Japan around 1933 and in the United States in 1939 ( IARC, 1982 ). WebThe leaching of di(2-ethylhexyl) phthalate from flexible plastics used in medical devices, such as during dialysis and transfusion, can result in large direct exposures. 5.2 Human carcinogenicity data. One small study of workers in a di(2-ethylhexyl) phthalate production plant did not show any excess of cancer mortality. djsbd

PUBLIC HEALTH STATEMENT Di(2-ethylhexyl)phthalate (DEHP)

WebCancer risk is predicted to be low (approximately five in a million). Conclusions There is no apparent public health hazard with recreational exposures to beach/intertidal surface ... Di-n-octyl phthalate 0.019 20,000 IM EMEG No 4,4’-DDD 0.027 2.9 B2 CREG No 4,4’-DDE 0.0058 2.1 B2 CREG No 4,4’-DDT 0.017 2.1 B2 CREG No ... WebDiisononyl phthalate (DINP) ... DINP is listed as a substance "known to the State of California to cause cancer" under Proposition 65 legislation. ... on March 7, 2024, that Di … WebJan 31, 1987 · Basis: Orally administered DEHP produced significant dose-related increases in liver tumor responses in rats and mice of both sexes. This may be a synopsis of the full weight-of-evidence narrative. Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (14 pp, 121 K) Oral Slope Factor: 1.4 x 10 -2 per mg/kg-day. djsbdj

A cancer risk assessment of di(2-ethylhexyl)phthalate

新型含卤污染物的环境暴露组与健康效应的毒理学机制_全球科研项 …

WebDEHP (Di(2-ethylhexyl)phthalate) is listed as a known chemical to cause cancer and toxicity in males. DEHP was removed and banned from being used in children’s toys due to its ability to be absorbed through the … WebOct 10, 2024 · The plasticizer di (2-ethylhexyl) phthalate (DEHP) and its hydrolysate mono (2-ethylhexyl) phthalate (MEHP) are major toxicants from plastics, but their association with hormone-dependent cancers has been controversial. djsbuzzWebOct 4, 2016 · Chemical Listed Effective December 20, 2013 as Known to the State of California to Cause Cancer: Diisononyl Phthalate (DINP) Hazard Identification … djsblog

"WebDEHP is on the Proposition 65 list because it can cause cancer and birth defects or other reproductive harm. Exposure to DEHP may increase the risk of cancer, and may also harm the male reproductive system. Exposure to DEHP during pregnancy may affect the … " - Di phthalate cancer

Di phthalate cancer

WebDiisononyl phthalate ( DINP) is a phthalate used as a plasticizer. DINP is typically a mixture of chemical compounds consisting of various isononyl esters of phthalic acid, and is commonly used in a large variety of plastic items. Health Issues [ edit] WebDi-n-butyl phthalate (DBP) is a plasticizer commonly used in industrial production and is present in our daily life. ... Low-dose mono(2-ethylhexyl) phthalate promotes ovarian cancer development through PPARalpha-dependent PI3K/Akt/NF-kappaB pathway. Sci. Total Environ., 790 (2024), Article 147990. View PDF View article View in Scopus Google ...

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WebExposure to: BBP (butyl benzyl phthalate) during pregnancy may affect the development of the child.; DBP (di-n-butyl phthalate) during pregnancy may affect the development of … WebDec 14, 2024 · What is di(2-ethylhexyl) phthalate (DEHP)? DEHP (CASRN 117-81-7) is part of a class of synthetic chemicals known as phthalates. Phthalates are used as solvents in household products and as plasticizers to make plastics more flexible and resilient. ... The International Agency for Research on Cancer has classified DEHP as possibly …

WebFeb 10, 2015 · In the past few years, researchers have linked phthalates to asthma, attention-deficit hyperactivity disorder, breast cancer, obesity and type II diabetes, low IQ, neurodevelopmental issues,... Web我国环境污染物的暴露特征复杂, 人群暴露途径和暴露剂量不清, 暴露所产生的健康危害研究缺乏理论和方法。项目以二恶英、四溴双酚a、全氟化合物、高氯酸盐和碘等含卤素类热点污染物为研究对象, 通过与基于生理学为基础的毒物动力学(pbtk)关联,在我国开展人群污染物环境及膳食内外暴露的分析 ...

Web(Note that di-n-octyl phthalate, however, is the name for a different chemical.) Trade names used for DEHP include Platinol DOP, Octoil, Silicol 150, Bisoflex 81, and Eviplast 80. ... WebJan 5, 2011 · Phthalate esters are a main group of plasticizers, including di- (2-ethylhexyl) phthalate (DEHP) and diisononyl phthalate (DINP) as the most widely used phthalates, which can be the subject of argument regarding their probable side effects on …

WebDongsheng Di 1 , Ruyi Zhang 1 , Haolong Zhou 1 , Muhong Wei 1 , Yuan Cui 1 ... High levels of mono-n-butyl phthalate, monobenzyl phthalate, and 1-napthol were significantly associated with increased risk of all cause, cardiovascular disease (CVD) and cancer mortality among all participants. WQS index was associated with the risks of all-cause ...

WebJul 2, 2010 · Some phthalates have been shown to cause cancer, liver toxicity, kidney toxicity, or reproductive problems in experimental animals. ... (Benzyl Butyl Phthalate or BBP) Toxicity Review for Di-n-butyl Phthalate (Dibutyl Phthalate or DBP) Toxicity Review for Di(2-ethylhexyl) Phthalate (DEHP) djsbuzz.inWebJul 15, 1999 · Di-(2-ethylhexyl)phthalate (DEHP) and its hydrolysis product mono-(2-ethylhexyl)phthalate (MEHP) have been examined for genotoxic activity on previous occasions. Only MEHP was found to cause chromosome damage in CHO cells but was without effect in the sister chromatid exchange and hypoxanthine guanine … djsboardshopWeb"This product can expose you to chemicals including Di- (2-ethyl hexyl) phthalate (DEHP) which is known to the state of California to cause cancer, birth defects, and other reproductive harm" and also a website that only contains information about exposure to formaldehyde and no information about DEHP. djsbuzz plannerWebThe current United States Environmental Protection Agency (EPA) classification of di(2-ethylhexyl)phthalate (DEHP) as a B2 "probable human" carcinogen is based on … djsbuzz 2021WebApr 7, 2004 · A cancer risk assessment of di(2-ethylhexyl)-phthalate: application of the new U.S. EPA risk assessment guidelines. Regul Toxicol Pharmacol. 1999; 29 (3):327–357. [Google Scholar] Foster PM, Mylchreest E, Gaido KW, Sar M. Effects of phthalate esters on the developing reproductive tract of male rats. Hum Reprod Update. 2001; 7:231–235. djsc no 6.864 pág: 01 data: 12.09.85WebMar 4, 2024 · Premature ovarian failure (POF) is defined as loss of ovarian function in women less than 40 years of age. The causes of POF are diverse and include environmental factors. Di-2-ethylhexyl phthalate (DEHP) is one factor that may cause POF. The ubiquitin-proteasome system maintains intracellular balance by promoting or … djsbuzz inWebDi(2-ethylhexyl)phthalate (DEHP) may cause carcinogenicity in the liver; however, few have detailed on the potential effects of DEHP exposure on colorectal cancer. Male Sprague … djsc30