WebJan 16, 2024 · Shaji Kumar, MD Investigators are taking a personalized approach to treating patients with multiple myeloma (MM) by introducing novel agents in combination with backbone chemotherapies,... WebNov 30, 2024 · Multiple myeloma (MM) is a plasma cell malignancy for which there is currently no cure. While treatment options for MM have expanded over the last two decades, all patients will eventually become resistant to current therapies. Thus, there is an urgent need for novel therapeutic strategies to treat MM. The isoprenoid biosynthetic pathway …
Pomalidomide: a novel drug to treat relapsed and refractory …
WebAug 6, 2024 · It is a novel peptide conjugate, ultimately a melphalan-derived warhead (melflufen flufenamide) that rapidly delivers its payload directly into the tumor cell. The drug conjugate is highly lipophilic and therefore safe, and readily enters the bone marrow. WebDec 9, 2024 · IMiDs plus novel agent combinations The IMiDs lenalidomide and pomalidomide have helped transform the management of MM. Lenalidomide is a current … china hydraulic power station suppliers
Approved Combinations and Novel Agents Expand Therapy …
Web1 day ago · Apr 13, 2024. Jordyn Sava. In an interview with Targeted OncologyTM, Ajay Nooka, MD, discussed findings from the phase 3 KarMMa-3 trial and the use of ide-cel for the treatment of patients with relapsed/refractory multiple myeloma. Idecabtagene vicleucel (ide-cel; Abecma) prolonged progression-free survival (PFS) and improved response … WebNov 13, 2024 · Discussions and Conclusions: This review highlights the need for ongoing research into cost effectiveness of novel agents in multiple myeloma. In general, novel agents are considered cost effective, however; there were a relatively small number of papers ion this topic and conclusions should be drawn with caution regarding the cost ... Web1 day ago · OM-301 has received an orphan drug designation from the FDA for the treatment of patients with multiple myeloma, according to Oncolyze. 1. OM-301 is an investigational … grahams protein pouch