Shnrf2
Web11 Feb 2016 · NRF2 (nuclear factor erythroid-derived 2-like 2) plays an important role in defense against oxidative stress at the cellular level. Recently, the roles of NRF2 in … Web19 Sep 2024 · NRF2 is a master regulator of the antioxidative response that was recently proposed as a potential regulator of extracellular matrix (ECM) gene expression. Fibroblasts are major ECM producers in all connective …
Shnrf2
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Web8 Jul 2024 · NRF2 silencing in T98G cells (T98G-shNRF2) significantly reduced the viability upon TMZ treatment. On the other hand, T98G-shNRF2 was resistant to ferroptosis and reverted intracellular GSH levels, indicating that NRF2 plays a key role in ferroptosis induction through GSH modulation. Web20 Feb 2024 · Nuclear factor erythroid-2-related factor-2 (Nrf2 or NFE2L2) is a master regulator of the anti-oxidative stress response, which is involved in the defense against many oxidative stress/inflammation-mediated diseases, including anticancer effects elicited by an increasing number of natural products.
WebshNRF2v1 gRNA/shRNA sequence AGAGCAAGATTTAGATCATTTCTGCAGAAATGATCTAAATCTTGCTCT Species H. sapiens … Web11 Jan 2024 · Animal experimental procedures were approved by the Medical Ethics Committee of Zhejiang Provincial People’s Hospital. The six-week-old male mice were randomized into different groups. T47D shControl and T47D shNRF2 cells (5 × 10 6 cells/mice) were implanted subcutaneously into the flank of nude mice. After tumor …
Web27 Nov 2024 · As shown in Fig. 5A, there was a substantial decrease in NRF2 protein levels in the A549 shNRF2 cell line, while the overexpression was capable of raising the amount …
Web1 Dec 2024 · The MTT assay indicated that these high-cNrf2-expressing shNrf2-HCT116 stable clones exhibited the lowest percentage survival when treated with RV-59 than with …
Web31 Aug 2024 · As shown in Figure 7A, stable cell lines named NIH3T3_vGPCR-shNrf2-2 and NIH3T3_vGPCR-shNrf2-2.1 showed lower levels of Nrf2 expression when compared with NIH3T3_vGPCR. We injected 1x10 6 NIH3T3_vGPCR (control) or NIH3T3_vGPCR–shNrf2-2.1 cells into the right flank of six and five nude mice, respectively, and observed the mice … michal onuferWeb27 Nov 2024 · As shown in Fig. 5A, there was a substantial decrease in NRF2 protein levels in the A549 shNRF2 cell line, while the overexpression was capable of raising the amount of the transcription factor in ... how to charge a blackweb portable chargerWeb26 Nov 2024 · In shNRF2 A549 cells, the mRNA levels of NRF2 and its target AKR1C1, GCLC, NQO1, and HO-1 were significantly lower than those in the nonspecific shRNA control … michaloma housingWeb22 May 2024 · The efficient shNRF2 used are: human ATTTCACATCACAGTAGGAGC, mouse ATTAAGACACTGTAATTCGGG. Lentiviruses were collected after 48 h transfection, and … michal old testamentWeb20 Feb 2024 · The efficiency of shMock and shNrf2 in JB6 P+ cells was examined and the protein expression of Nrf2 was significantly reduced in shNrf2 JB6 P+ cells in Figure 7A … michal ondracekWeb8 Aug 2024 · The pGL3-ARE-luc vector was generated by inserting three copies of the antioxidant response element (ARE; 5'-GTGACAAAGCAATCCCGT GACAAAGCAATCCCGTGACAAAGCAATA-3') into pGL3-basic luciferase reporter plasmid. pLV-H1-SGIPZ-shNRF2 was constructed by inserting NRF2 shRNA into lentiviral pLV-H1 … michalowo facebookWebDMF and shNRF2 modulates γ-globin gene expression in human normal erythroid progenitors. (A) Erythroid progenitors generated in liquid culture system from CD34 + stem cells were treated at day 8 with 200 μM dimethyl fumarate (DMF) for 48 hours. michal oqbe